Turkiye Klinikleri Journal of Dermatology

.: CASE REPORTS
Acute Onset of Generalize Pustular Psoriasis in a Patient with Previously Unknown HIV Infection
HIV Enfeksiyonu Olduğu Önceden Bilinmeyen Bir Hastada Akut Jeneralize Püstüler Psöriyazis Manifestasyonu
Ali TÜRKAYa, Yuliia PAVLIVNA KARVATSKAa, Olha IVANIVNA DENYSENKOa
aDepartment of Dermatoveneorolog, Bukovinian State Medical of University (BSMU), Chernivtsi, UKRAINE
Turkiye Klinikleri J Dermatol. 2019;29(2):80-4
doi: 10.5336/dermato.2018-63989
Article Language: EN
Full Text
ABSTRACT
 HIV is epidemic in Ukraine and at the end of 2017, the total official number was reported to be 42700 cases. Approximately, 90% of HIV positive patients develop various types of skin diseases. Especially, patients with psoriasis and HIV infection often present with more severe and treatment-refractory cutaneous disease. We describe a patient with first manifestation of pustular psoriasis with previously unknown HIV infection. A 35 years-old male was admitted to our clinic with severe pustular psoriasis eruption which first emerged two months ago. The patient?s HIV antibody test was positive. Psoriasis manifestations can be severe in patients with acquired immune deficiency syndrome (AIDS). Physicians may face diagnostic and therapeutic difficulties when psoriasis coexists with HIV infection. The HIV test should be considered in patients affected by severe erythrodermic psoriasis and resistant to conventional and biological treatments.

Keywords: Pustular psoriasis; HIV infection; AIDS
ÖZET
 Ukrayna'da insan immün yetmezlik virüsü (HIV) epidemik olup, 2017 yılının başında resmi olarak açıklanan toplam sayı 42700 vakadır. HIV pozitif olan hastaların yaklaşık %90'ında bazı deri hastalıkları gelişir. Özellikle HIV enfeksiyonu bulunan hastalarda, psöriyazis daha ciddi ve tedaviye dirençli bir deri hastalığı olarak karşımıza çıkar. Burada, ilk kez püstüler psöriyazis tanısı alan ve daha önce HIV pozitifliği bilinmeyen bir hastanın vaka sunumunu yaptık. Otuzbeş yaşında erkek hasta kliniğimize 2 ay önce ilk kez ortaya çıkan ciddi püstüler psöriyazis nedeniyle başvurdu, HIV antikor testi sonucu pozitif olarak gelen hastanın HIV pozitifliğinden daha önce haberi olmadığı öğrenildi. Edinsel immün yetmezlik sendromlu hastalarda psöriyazis ciddi seyirli olabildiği gibi, klinisyenler tanıda ve tedavide HIV enfeksiyonu ile birlikte bulunan psöriyazis hastalarında zorluklarla karşılaşabilirler. Bu vaka dolayısıyla HIV araştırılmasının özellikle ciddi, eritrodermik, konvansiyonel ve biyolojik tedavilere dirençli vakalarda önemini vurgulamak istedik.

Anahtar Kelimeler: Psöriyazis; HIV; Edinilmiş immünyetmezlik sendromu
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