.: ORİJİNAL ARAŞTIRMA
Choroidal Vascularity Index Changes in Different Body Mass Index Groups: Case-Control Study
Farklı Beden Kitle İndeksi Gruplarında Koroid Vaskülarite İndeksi Değişiklikleri: Olgu Kontrol Çalışması
Turkiye Klinikleri J Ophthalmol. 2023;32(1):21-7
doi: 10.5336/ophthal.2022-91796
Makale Dili: EN
Tam Metin
ABSTRACT
Objective: Comparing Choroidal Vascularity Index (CVI) values in groups with different body mass index (BMIs). Material and Methods: In this prospective study, we compared choroidal thickness (CT) and CVI values of those with different BMI. The weight and height of all patients were measured, and BMI was calculated. All volunteers were examined with a detailed eye examination. In addition, enhanced depth imaging optical coherence tomography (EDI-OCT) of all individuals was evaluated. Results: The study included 157 right eyes of 157 volunteers. Of these, 30 were normal, 30 were overweight, 30 were class 1 obese, 22 were class 2 obese, and 45 were morbidly obese. CVI and CT of all groups were compared with EDI-OCT. There was a statistically significant difference in CT between the groups in the temporal CT 500 μm, temporal CT 1,000 μm, temporal CT 1,500 μm, and nasal CT 500 μm regions (p<0.005). The CVI and luminal area/stromal area (LA/SA) groups also found a statistically significant difference (p<0.005). In the correlation analysis with BMI, a statistically significant weak negative correlation was found between BMI, CVI, and LA/SA (r=-0.304, p<0.001 and r=-0.255, p=0.001, respectively). In addition, a positive correlation was found between BMI in temporal CT 500 μm, temporal CT 1,000 μm and temporal CT 1,500 μm and nasal CT 1,000 μm and nasal CT 1,500 μm measurements. Conclusion: There is a negative correlation between BMI and CVI. In addition, a statistically significant difference was found between the morbidly obese group and the normal weight BMI groups regarding choroidal structures.
Keywords: Choroid; optic coherence tomography; obesity
Objective: Comparing Choroidal Vascularity Index (CVI) values in groups with different body mass index (BMIs). Material and Methods: In this prospective study, we compared choroidal thickness (CT) and CVI values of those with different BMI. The weight and height of all patients were measured, and BMI was calculated. All volunteers were examined with a detailed eye examination. In addition, enhanced depth imaging optical coherence tomography (EDI-OCT) of all individuals was evaluated. Results: The study included 157 right eyes of 157 volunteers. Of these, 30 were normal, 30 were overweight, 30 were class 1 obese, 22 were class 2 obese, and 45 were morbidly obese. CVI and CT of all groups were compared with EDI-OCT. There was a statistically significant difference in CT between the groups in the temporal CT 500 μm, temporal CT 1,000 μm, temporal CT 1,500 μm, and nasal CT 500 μm regions (p<0.005). The CVI and luminal area/stromal area (LA/SA) groups also found a statistically significant difference (p<0.005). In the correlation analysis with BMI, a statistically significant weak negative correlation was found between BMI, CVI, and LA/SA (r=-0.304, p<0.001 and r=-0.255, p=0.001, respectively). In addition, a positive correlation was found between BMI in temporal CT 500 μm, temporal CT 1,000 μm and temporal CT 1,500 μm and nasal CT 1,000 μm and nasal CT 1,500 μm measurements. Conclusion: There is a negative correlation between BMI and CVI. In addition, a statistically significant difference was found between the morbidly obese group and the normal weight BMI groups regarding choroidal structures.
Keywords: Choroid; optic coherence tomography; obesity
ÖZET
Amaç: Farklı beden kitle indeksine (BKİ) sahip bireylerde koroid vaskülarite indeksi (KVİ) değerlerinin karşılaştırılması. Gereç ve Yöntemler: Bu prospektif çalışmada, farklı BKİ'ye sahip kişilerin koroid kalınlığı (KK) ve KVİ değerlerini karşılaştırdık. Tüm hastaların kilo ve boyları ölçüldü ve BKİ hesaplandı. Tüm gönüllüler detaylı göz muayenesi ile muayene edildi. Ayrıca tüm bireylerin gelişmiş derinlik görüntülemeli optik koherens tomografisi [enhanced depth imaging optical coherence tomography (EDI-OCT)] değerlendirildi. Bulgular: Çalışmaya 157 gönüllünün 157 sağ gözü dâhil edildi. Bunların 30'u normal kilolu, 30'u fazla kilolu, 30'u 1. sınıf obez, 22'si 2. sınıf obez ve 45'i morbid obez idi. Tüm grupların KVİ ve KK'si EDI-OCT ile karşılaştırıldı. KK temporal 500, KK temporal 1.000, KK temporal 1.500 ve KK nazal 500 bölgelerinde gruplar arasında KK açısından istatistiksel olarak anlamlı fark vardı (p<0,005). Ayrıca KVİ ve 'luminal area/stromal area (LA/SA)' açısından gruplar arasında istatistiksel olarak anlamlı fark bulundu (p<0,005). BKİ ile korelasyon analizinde BKİ, KVİ ve LA/SA arasında istatistiksel olarak anlamlı negatif zayıf korelasyon bulundu (sırasıyla r=-0,304, p<0,001 ve r=-0,255, p=0,001). Ayrıca BKİ ile KK temporal 500, KK temporal 1.000 ve KK temporal 1.500 ile KK nazal 1.000 ve KK nazal 1.500 ölçümleri arasında pozitif korelasyon bulundu. Sonuç: BKİ ve KVİ arasında negatif bir ilişki vardır. Ayrıca morbid obez grup ile normal kilolu BKİ grupları arasında koroid yapıları açısından istatistiksel olarak anlamlı fark bulundu.
Anahtar Kelimeler: Koroid; optik koherens tomografi; obezite
Amaç: Farklı beden kitle indeksine (BKİ) sahip bireylerde koroid vaskülarite indeksi (KVİ) değerlerinin karşılaştırılması. Gereç ve Yöntemler: Bu prospektif çalışmada, farklı BKİ'ye sahip kişilerin koroid kalınlığı (KK) ve KVİ değerlerini karşılaştırdık. Tüm hastaların kilo ve boyları ölçüldü ve BKİ hesaplandı. Tüm gönüllüler detaylı göz muayenesi ile muayene edildi. Ayrıca tüm bireylerin gelişmiş derinlik görüntülemeli optik koherens tomografisi [enhanced depth imaging optical coherence tomography (EDI-OCT)] değerlendirildi. Bulgular: Çalışmaya 157 gönüllünün 157 sağ gözü dâhil edildi. Bunların 30'u normal kilolu, 30'u fazla kilolu, 30'u 1. sınıf obez, 22'si 2. sınıf obez ve 45'i morbid obez idi. Tüm grupların KVİ ve KK'si EDI-OCT ile karşılaştırıldı. KK temporal 500, KK temporal 1.000, KK temporal 1.500 ve KK nazal 500 bölgelerinde gruplar arasında KK açısından istatistiksel olarak anlamlı fark vardı (p<0,005). Ayrıca KVİ ve 'luminal area/stromal area (LA/SA)' açısından gruplar arasında istatistiksel olarak anlamlı fark bulundu (p<0,005). BKİ ile korelasyon analizinde BKİ, KVİ ve LA/SA arasında istatistiksel olarak anlamlı negatif zayıf korelasyon bulundu (sırasıyla r=-0,304, p<0,001 ve r=-0,255, p=0,001). Ayrıca BKİ ile KK temporal 500, KK temporal 1.000 ve KK temporal 1.500 ile KK nazal 1.000 ve KK nazal 1.500 ölçümleri arasında pozitif korelasyon bulundu. Sonuç: BKİ ve KVİ arasında negatif bir ilişki vardır. Ayrıca morbid obez grup ile normal kilolu BKİ grupları arasında koroid yapıları açısından istatistiksel olarak anlamlı fark bulundu.
Anahtar Kelimeler: Koroid; optik koherens tomografi; obezite
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